For most autoimmune diseases there are clear sex differences in prevalence whereby females are generally more frequently affected than males (Eaton et al., 2007).This gender bias can be modest, as is seen in MS (Bentzen et al., 2010, Cheng et al., 2009, El Adssi et al., 2012, Hadjimichael et al., 2008, McCombe, 2003, Osoegawa et al., …